Finnish to English Medical Medical (general)

is it induced or indicated?

Here is the Finnish

Metastaattisen rintasyövän hoito monoterapiana potilailla, joiden metastaattisen sairauden ensilinjan hoito on epäonnistunut ja joille vakiintunut antrasykliiniä sisäl- tävä hoito ei ole indisoitu

The treatment of metastatic breast cancer as a monotherapy in patients whose first-line treatment of metastatic disease has failed and for whom established anthracycline-based therapy has not been induced/indicated (?)

many thanks in advance

Spencer