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It is generally accepted that most stem cells are ***quiescent*** and only a few stem cells supply all the blood cells at a given time.

The ability of a cell to respond to a specific set of signals determines whether the cell will live or die, differentiate, proliferate, or remain ***quiescent***.

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Note added at 9 mins (2004-05-12 17:00:20 GMT)
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... after P+I, 43±1.8% of quiescent cells [P<0.01versus ***quiescent cells***]; after 10% FBS, 55±7.7 ... mL gentamicin, 50 ng/mL amphotericin B, and 5 µg/mL ...
atvb.ahajournals.org/cgi/content/full/20/5/1216


J. Antimicrob. Chemother. -- Rogers et al. 51 (2): 305
... that, unlike its effects on mammalian cells, the toxicity of amphotericin B against C.albicans is not ... medium) than it is if the ***cells are quiescent***, but metabolically active ...
www.jac.oupjournals.org/cgi/content/full/51/2/305


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Note added at 1 day 4 hrs 3 mins (2004-05-13 20:53:58 GMT)
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Безусловно, амфотерицин активен в отношении самих паразитов, а не тех клеток, внутри которых эти паразиты могут находиться. Для этого достаточно как следует порыться в интернете, например здесь:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
Набираете key words
amastigote AND amphotericin AND leishmaniasis
or
mechanism AND amphotericin AND leishmaniasis

Одна из статей: http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pub...
Вторую цитирую:
AmBisome: liposomal formulation, structure, mechanism of action and pre-clinical experience.

Adler-Moore J, Proffitt RT.

Department of Biological Sciences, California State Polytechnic University, 3801 West Temple Avenue, Pomona, CA 91768, USA. [email protected]

Amphotericin B is the treatment of choice for life-threatening systemic fungal infections such as candidosis and aspergillosis. To improve this drug\'s efficacy and reduce its acute and chronic toxicities, several lipid formulations of the drug have been developed, including AmBisome, a liposomal formulation of amphotericin B. ...AmBisome can bind to fungal cell walls, where the liposome is disrupted. The amphotericin B, after being released from the liposomes, is thought to transfer through the cell wall and bind to ergosterol in the fungal cell membrane. This mechanism of action of AmBisome results in its potent in vitro fungicidal activity while the integrity of the liposome is maintained in the presence of mammalian cells, for which it has minimal toxicity. In animal models, AmBisome is effective in treating both intracellular (leishmaniasis and histoplasmosis) and extracellular (candidosis and aspergillosis) systemic infections. ...

Речь идет о делящихся/размножающихся паразитах и о паразитах в стадии покоя. Паразиты одноклеточные, поэтому их называют клетками.
Многие антибиотики по механизму действия похожи на противоопухолевые препараты (цитостатики). А вот что известно о цитостатиках (цитата из Harrison\'s Principles of Internal Medicine и его русского перевода):

Many chemotherapeutic agents, such as the antimetabolites and the alkylating agents, are cell-cycle-active; that is, they are cytotoxic mainly to actively cycling cells. In addition, some cycle-active agents are phase-specific; that is, they are cytotoxic to cells in a particular phase of the cell cycle. Other agents are capable of exerting cytotoxicity at any phase of cell cycle, including G0/G1, and are not considered cycle-active.
Многие противоопухолевые средства, в частности антиметаболиты и алкилирующие средства, оказывают цитотоксическое действие главным образом на клетки, проходящие митотический цикл. Действие некоторых из них привязано к определенным периодам митотического цикла; такие препараты называют фазоспецифическими. Остальные препараты оказывают цитотоксическое действие в любом периоде клеточного цикла, включая периоды G0 и G1.

Клетки, находящиеся в периоде G0, называют quiescent. Еще цитата:

¶Quiescent (¶G0) but can enter the cell cycle if appropriately stimulated
Покоящиеся клетки — это клетки, которые при определенных условиях могут начать делиться.

Интернет: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/Cel...

G0
Many times a cell will leave the cell cycle, temporarily or permanently. It exits the cycle at G1 and enters a stage designated G0 (G zero). A G0 cell is often called \"quiescent\", but that is probably more a reflection of the interests of the scientists studying the cell cycle than the cell itself. Many G0 cells are anything but quiescent. They are busy carrying out their functions in the organism. e.g., secretion, attacking pathogens.